Valence is building the world’s most powerful chemistry engine. The company has pioneered the application of few-shot learning in drug design, along with the development of best-in-class AI methods for molecular representation, structure and ligand-based de novo design, and multiparameter optimization, enabling the design of novel chemistry against previously intractable biology. Valence’s AI-based generative chemistry engine has been extensively validated and is being used to identify and design drug candidates in collaboration with industry-leading partners.