adMare Industry Builder Series webinar featuring Dr. Joel S. Freundlich: Engineering Platforms for Infectious Disease Research

Join us on Monday, October 21st, for an adMare Industry Builder Series webinar featuring Dr. Joel S. Freundlich where he will discuss Engineering Platforms for Infectious Disease Research.

A combination of computational, chemical, and biological techniques may be utilized to discover and then optimize small molecule agents against infectious diseases of global health significance. In this webinar, Dr. Freundlich will present a structure-based design approach that has been leveraged to solve a pharmacokinetic deficit in an indazole series of antituberculars.  He will explain how machine learning strategies have been deployed to discover and then optimize small molecule anti-infectives with an eye toward multiple-criteria decision making. This platform was able to quantify the accumulation of small molecules within their targeted cell type, in addition to the identification of intracellular metabolites.

About Dr. Joel S. Freundlich

Dr. Joel S. Freundlich is a Professor of Pharmacology, Physiology and Neuroscience and of Medicine at Rutgers University–New Jersey Medical School. Prior to his return to academic research, he spent eight years in the pharmaceutical industry as a medicinal chemist. His undergraduate and master’s degree training were in chemical engineering at Cornell University as a McMullen Dean’s Scholar. He received his doctorate in organic chemistry from the Massachusetts Institute of Technology under the tutelage of 2005 Nobel Prize in Chemistry awardee Richard Schrock.